Blistex Healing Relief Cream. Blistex Relief Cream is a penetrating and soothing remedy to relieve and treat occasional cold sores and cracked and chapped lips, leaving your lips feeling soft again. Cold Sores - when first symptoms arise, gently apply every hour to rapidly relieve any discomfort. You are more vulnerable to developing a cold sore if you are feeling stressed and rundown. Lip Care - your lips are more sensitive during extreme weather conditions, so may need a little more care than normal. Apply Blistex Relief Cream frequently to quickly relieve sore, cracked and chapped lips. Formerly known as Blisteze. Medicated relief for occasional cold sores, cracked, chapped and sore lips.