PharmaClinix Lightenex Plus Face Cream. Lightenex Plus cream is a new powerful, extra strength formulation, which has been especially developed to address the problem of very dark & resistant hyperpigmentation. Lightenex Plus cream is particularly excellent for very dark skin tones (darker Asians & African skins). Lightenex Plus contains a unique blend of the latest scientifically developed skin lightening agents that are completely safe and produced according to the stringent EU regulations.